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Scientists unlock virus-fighting power with synthetic nanobody platform

Discovery and validation of nanobodies, a promising class of biologics, for viral infection prevention and treatment, including anti-SARS-CoV-2 nanobodies with enhanced neutralization properties through synergistic pairing. The study demonstrates the potential of nanobodies in developing effective therapies against viral infections.

8 Jun 2023

Seaweed farming may help solve global hunger and malnutrition

To help solve hunger and malnutrition while also slowing climate change, some farmers could shift from land to sea, suggests a recent study from the Friedman School of Nutrition Science and Policy at Tufts University.

8 Jun 2023

Biologists discover a previously unknown way that the immune system detects viruses

Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs.

8 Jun 2023

Cryo-EM reveals key atomic structures of the ends of actin filament

Actin filaments -; protein structures critical to living movement from single cells to animals -; have long been known to have polarity associated with their physical characteristics, with growing "barbed" and shrinking "pointed" ends.

8 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Study uncovers novel mechanisms underlying plant immunity against major root disease

Researchers led by CHEN Yuhang and ZHOU Jianmin from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have shown how plants resist clubroot, a major root disease that threatens the productivity of Brassica crops such as rape.

8 Jun 2023

Study shows how blood makes the brain’s immune cells toxic

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive dysfunction and motor impairment.

8 Jun 2023

Study provides a new perspective on the aberrant nature of B cell phenotypes in skin cancer

A new study that sheds light on how B cells react to skin cancer cells could pave the way for innovative therapy design.

8 Jun 2023

DNA study sheds light on how we maintain healthy blood sugar levels after meals

A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes.

8 Jun 2023

Penn Medicine researchers receive $6 million NIH grant to gain new insights on cardiac cellular identity

Historically, scientists have studied how cells develop and give rise to specialized cells, such as heart, liver, or skin cells, by examining specific proteins.

8 Jun 2023

Scientists identify the IL-17 protein as a determining factor in skin aging

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin aging.

8 Jun 2023

Study examines the combined toxicity of common environmental pollutants on the gut-brain axis

Regulating environmental pollution around the world still largely relies upon risk assessments of "single pollutants," ignoring combined toxicities and interactions of groups of substances.

8 Jun 2023

Teaming up with the patient’s immune system to combat cancer

The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage.

8 Jun 2023

SARS-CoV-2 virus can cause brain cells to fuse: Study

Researchers at The University of Queensland have discovered viruses such as SARS-CoV-2 can cause brain cells to fuse, initiating malfunctions that lead to chronic neurological symptoms.

8 Jun 2023

New process can help to design drugs with fewer or no side effects

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane.

7 Jun 2023

Newborn genome sequencing project identifies unanticipated disease risks

Genomic sequencing of newborns reveals unanticipated genetic risks, prompting actionable medical interventions and potential life-saving care for infants and their families. This study highlights the value of comprehensive sequencing in newborns for early detection and management of genetic conditions.

7 Jun 2023

Life Science News

Scientists unlock virus-fighting power with synthetic nanobody platform

Seaweed farming may help solve global hunger and malnutrition

Biologists discover a previously unknown way that the immune system detects viruses

Cryo-EM reveals key atomic structures of the ends of actin filament

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Study uncovers novel mechanisms underlying plant immunity against major root disease

Study shows how blood makes the brain’s immune cells toxic

Study provides a new perspective on the aberrant nature of B cell phenotypes in skin cancer

DNA study sheds light on how we maintain healthy blood sugar levels after meals

Penn Medicine researchers receive $6 million NIH grant to gain new insights on cardiac cellular identity

Scientists identify the IL-17 protein as a determining factor in skin aging

Study examines the combined toxicity of common environmental pollutants on the gut-brain axis

Teaming up with the patient’s immune system to combat cancer

SARS-CoV-2 virus can cause brain cells to fuse: Study

New process can help to design drugs with fewer or no side effects

Newborn genome sequencing project identifies unanticipated disease risks

Middle-brain region linked to emotion control likely prompts females to kill their young

Unlocking the complete potential of industrial hemp using genomics

DNAmFitAge: A new method to incorporate physical fitness into epigenetic clocks

Ancient, virus-like protein may contribute to ALS

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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